Project Description

IDAMS – International Research Consortium on Dengue Risk Assessment, Management and Surveillance

Dengue fever, an infectious disease spread by the Aedes mosquito, has placed a significant strain on the healthcare system in endemic countries such as Indonesia. Early detection of dengue is critical for improving case management and making the best use of limited health resources. However, making an accurate diagnosis of dengue before any complications arise is difficult, especially in healthcare settings with limited resources. Late intervention may result in death and increase the likelihood of dengue outbreaks.


Funding


Partnering Countries


Duration

2011 – 2017


Principal Investigator

Ida Safitri Laksanawati


The IDAMS project was a collaboration of experts from nineteen research institutions around the world, including Indonesia. The study’s goal was to improve dengue diagnosis and clinical management. Previous clinical and laboratory parameters, as well as viral and immunological markers, must be identified. Within three days of fever onset, this will aid in distinguishing dengue from other common feverish illnesses. Identify any available features that predict the likelihood of progressing to a more severe disease course. IDAMS has published 52 journal articles, five book chapters, and two reports.

Publications

Jaenisch, T., Tam, D. T. H., Kieu, N. T. T., Van Ngoc, T., Nam, N. T., Van Kinh, N., Yacoub, S., Chanpheaktra, N., Kumar, V., See, L. L. C., Sathar, J., Sandoval, E. P., Alfaro, G. M. M., Laksono, I. S., Mahendradhata, Y., Sarker, M., Ahmed, F., Caprara, A., Benevides, B. S., . . . Wills, B. (2016). Clinical evaluation of dengue and identification of risk factors for severe disease: protocol for a multicentre study in 8 countries. BMC Infectious Diseases, 16(1). https://doi.org/10.1186/s12879-016-1440-3

Stahl, H. C., Butenschoen, V. M., Tran, H. T., Gozzer, E., Skewes, R., Mahendradhata, Y., Runge-Ranzinger, S., Kroeger, A., & Farlow, A. (2013). Cost of dengue outbreaks: literature review and country case studies. BMC Public Health, 13(1). https://doi.org/10.1186/1471-2458-13-1048

Badurdeen, S., Valladares, D. B., Farrar, J., Gozzer, E., Kroeger, A., Kuswara, N., Ranzinger, S. R., Tinh, H. T., Leite, P., Mahendradhata, Y., Skewes, R., & Verrall, A. (2013). Sharing experiences: towards an evidence based model of dengue surveillance and outbreak response in Latin America and Asia. BMC Public Health, 13(1). https://doi.org/10.1186/1471-2458-13-607

Farrar, J. J., Hien, T. T., Horstick, O., Hung, N. T., Jaenisch, T., Junghanns, T., Kroeger, A., Laksono, I. S., Lum, L., Martinez, E., Simmons, C. P., Tami, A., Tomashek, K. M., & Wills, B. A. (2013). Dogma in Classifying Dengue Disease. The American Journal of Tropical Medicine and Hygiene, 89(2), 198–201. https://doi.org/10.4269/ajtmh.13-0157

Akbar, N. A., Allende, I., Balmaseda, A., Coelho, I. C. B., da Cunha, R. V., Datta, B., Shamala Devi, S., Farrar, J., Gaczkowski, R., Guzman, M. G., Harris, E., Hien, T. T., Horstick, O., Hung, N. T., Janisch, T., Junghanss, T., Kroeger, A., Laksono, I. S., Lum, L. C. S., . . . Wills, B. (2012). Regarding “Dengue–How Best to Classify It.” Clinical Infectious Diseases, 54(12), 1820–1821. https://doi.org/10.1093/cid/cis328

The Project Team